X-linked Hydrocephalus (Bickers-Adams syn drome) in Siblings.

X-linked Hydrocephalus (Bickers-Adams syn drome) in Siblings.

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Summary: A family with three consecutive male children with prenatal hydrocephalus is reported.The proband had prenatal hydrocephalus, bilateral flexion-adduction deformity of the thumbs and spas ticity.Exclusion of other causes of prenatal hydrocephalus on clinical Younger Looking Skin grounds, implicated X-linked hydrocephalus (Bickers-Adams syndrome) as the most probable diagnosis.

Since identification of an X-linked hydrocephalus has important conse quences for genetic counselling, analysis of the family JOINT-PRO CONCENTRATE history of any male infant with overt hydrocephalus at birth, is therefore very important.